Giannino Del Sal Selected Research

trimethylguanosine synthase

1/2022

TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance.

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Giannino Del Sal Research Topics

Disease

51	Neoplasms (Cancer) 01/2022 - 05/2002
10	Breast Neoplasms (Breast Cancer) 12/2020 - 06/2013
5	Carcinogenesis 01/2020 - 05/2002
5	Neoplasm Metastasis (Metastasis) 01/2019 - 01/2015
3	Infections 12/2017 - 03/2010
3	Triple Negative Breast Neoplasms 01/2017 - 01/2016
2	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 12/2017 - 05/2015
2	Inflammation (Inflammations) 01/2017 - 04/2015
2	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2014 - 11/2011
2	Ataxia Telangiectasia (Louis Bar Syndrome) 06/2013 - 11/2011
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Premature Aging 01/2021
1	Fibrosis (Cirrhosis) 01/2019
1	Hepatitis B 12/2017
1	Hyperinsulinism (Hyperinsulinemia) 01/2017
1	Burkitt Lymphoma (Burkitt's Lymphoma) 04/2016
1	Ischemia 10/2015
1	Diabetic Angiopathies (Diabetic Angiopathy) 04/2015
1	Wilms Tumor (Wilm's Tumor) 12/2013
1	Genomic Instability 05/2013
1	Ovarian Neoplasms (Ovarian Cancer) 05/2013
1	Huntington Disease (Huntington's Disease) 11/2011

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2004
7	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2021 - 07/2004
7	Pharmaceutical PreparationsIBA 12/2020 - 01/2011
5	MicroRNAs (MicroRNA)IBA 01/2021 - 06/2013
5	Transcription Factors (Transcription Factor)IBA 08/2014 - 03/2003
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 03/2006
3	Phosphotransferases (Kinase)IBA 01/2022 - 11/2011
3	Oncogene Proteins (Oncogene Protein)IBA 01/2022 - 01/2015
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2019
2	eprenetapoptIBA 04/2018 - 01/2016
2	Genetic Markers (Genetic Marker)IBA 01/2018 - 11/2015
2	NF-kappa B (NF-kB)IBA 01/2018 - 04/2015
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2017 - 01/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 06/2010
2	AntigensIBA 01/2017 - 12/2013
2	EnzymesIBA 01/2017 - 03/2010
2	Proteasome InhibitorsIBA 01/2017 - 01/2016
2	Mutant Proteins (Protein, Mutant)IBA 01/2017 - 01/2015
2	Biological ProductsIBA 11/2014 - 05/2002
2	IntegrasesIBA 01/2014 - 03/2010
1	trimethylguanosine synthaseIBA 01/2022
1	Threonine (L-Threonine)FDA Link 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	UbiquitinIBA 01/2022
1	Ligases (Synthetase)IBA 01/2022
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2022
1	N(2),N(2),7-trimethylguanosineIBA 01/2022
1	AndrogensIBA 01/2022
1	telomerase RNA (bTR)IBA 01/2022
1	phytobacteriomycin (PBM)IBA 01/2022
1	TESIBA 01/2021
1	ChromatinIBA 01/2021
1	DNA Transposable Elements (Element, IS)IBA 01/2021
1	Liposomes (Liposome)IBA 01/2021
1	HeterochromatinIBA 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	Phenobarbital (Luminal)FDA Link 12/2020
1	human ERBB2 proteinIBA 12/2020
1	Haloperidol (Haldol)FDA LinkGeneric 01/2019
1	MethyltransferasesIBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	Auranofin (Ridaura)FDA Link 04/2018
1	Heme Oxygenase-1IBA 04/2018
1	AntioxidantsIBA 04/2018
1	ThioredoxinsIBA 04/2018
1	Aflatoxin B1 (Aflatoxin B)IBA 12/2017
1	quinone (benzoquinone)IBA 01/2017
1	EpitopesIBA 01/2017
1	NIMA-Interacting Peptidylprolyl IsomeraseIBA 01/2017
1	Insulin (Novolin)FDA Link 01/2017
1	Peptides (Polypeptides)IBA 01/2017
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2017
1	HLA-A*02:01 antigenIBA 01/2017
1	Protein SIBA 01/2017
1	Codon (Codons)IBA 04/2016
1	Cyclin BIBA 02/2016
1	Cyclin AIBA 02/2016
1	carfilzomibIBA 01/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2015
1	Dasatinib (BMS 354825)FDA Link 11/2015
1	IsomerasesIBA 10/2015
1	Bortezomib (Velcade)FDA Link 05/2015
1	CytokinesIBA 12/2014
1	ChemokinesIBA 12/2014
1	Mevalonic Acid (Mevalonate)IBA 04/2014
1	CateninsIBA 12/2013
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 05/2013
1	StathminIBA 05/2013
1	Huntingtin ProteinIBA 11/2011
1	Protein Kinases (Protein Kinase)IBA 11/2011

Therapy/Procedure

12	Therapeutics 01/2019 - 08/2008
2	Immunotherapy 01/2021 - 01/2017
2	Drug Therapy (Chemotherapy) 01/2019 - 11/2014
1	Investigational Therapies (Experimental Therapy) 01/2021